Hormonal Changes: in girls and women, these changes can make gums more sensitive and make it easier for gingivitis to develop.
Diabetes: People with diabetes are at a higher risk for develping infections, including gum disease.
Other Illnesses: Diseases like cancer or aids and their and their treatments can also negatively affect the health of the gums.
Medications: There are hundreds of prescription and over the counter medications that can reduce the flow of saliva, which has a protective affect on the mouth. Without enough saliva, the mouth is vulnerable to infections such as gum disease. And some medicines can cause abnormal overgrowth of the gum tissue: this can make it difficult to keep teeth and gums clean.
Genetic Susceptibility: Some people are more prone to gum disease than others.